Regulation of Energy Metabolism Group —— Principal Investigator
Name:
JIN, Wan-Zhu
Subject:
Wild Animal Nutrition and Reproduction
Tel/Fax:
+86-10-64806302  / 
E-mail:
jinw@ioz.ac.cn
Address:
Key Laboratory of Animal Ecology and Conservation Biology, Chinese Academy of Sciences, 1Beichen West Road, Chaoyang District, Beijing 100101, P.R. China
More:
Regulation of Energy Metabolism Group    中文
Resume:

Prof. Wanzhu Jin,  Group leader of Wild Animal Nutrition and Reproduction group; Key Laboratory of Animal Ecology and Conservation Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing, PR China.

1999-2003, Ph.D. United Graduate School of Veterinary Sciences, Gifu University, Japan

1990-1994, BSc. Department of Veterinary Medicine,Yanbian University,Jilin

Professional Experience:

2010-, Professor at Institute of Zoology, Chinese Academy of Sciences

2006-2010, Postdoc,Harvard Medical School

2003-2006, Postdoc Riken Institute, Japan

Research Interests:

Our major interest is to investigate relationship between energy metabolism and reproduction. Currently, we are focusing on 1, Molecular mechanism of brown adipose tissue differentiation/trans-differentiation; 2, From evolutional and ecological aspect, we apply multiple approaches such as genomic analysis, whole body KO mice, tissue specific KO mice, cellular and molecular techniques to try to understand how energy metabolism and reproduction is tightly connected and affect each other. 

Selected Publications:
  • Xiaomeng Liu, Siping Wang, Yilin You, Minghui Meng, Zongji Zheng,Meng Dong, Jun Lin, Qianwei Zhao, Chuanhai Zhang, Xiaoxue Yuan,Tao Hu, Lieqin Liu, Yuanyuan Huang, Lei Zhang, Dehua Wang,Jicheng Zhan, Hyuek Jong Lee, John R Speakman, and Wanzhu Jin. Brown adipose tissue transplantation reverses obesity in Ob/Ob mice. Endocrinology. 10.1210/en.2014-1598.
  • Yanyan Shen, et al. (2014). Recent advances in brown adipose tissue biology. Chin. Sci. Bull.59(31):4030–4040.
  • Liu X, Zheng Z, Zhu X, Meng M, Li L, Shen Y, Chi Q, Wang D, Zhang Z, Li C, Li Y, Xue Y, Speakman J and Jin W (2013). Brown adipose tissue transplantation improves whole-body energy metabolism. Cell Research 6: 851-854.
  • Jin W, Goldfine A, Boes T, Henry R, Ciaraldi T, et al. (2011) Increased SRF transcriptional activity is a novel signature of insulin resistance in humans and mice. Journal of Clinical Investigation121: 918–929.
  • Maekawa T,Jin W, Ishii S (2010) ATF2/ATFa regulate BMP induced adipogenesis. Molecular Cellular Biology 30: 613-25.
  • Jin W, Patti ME (2009) Genetic determinants and molecular pathways in the pathogenesis of diabetes. Clinical Science (Lond). 116: 99-111. Invited Review.
  • Jin W, Takagi T, Kanesashi S, Kurahashi T, Nomura T, et al. (2006) Schnurri-2 controls BMP-dependent adipogenesis via interaction with Smad proteins. Developmental Cell 10: 461-471.

Patents:  

  • Patti ME, Wanzhu Jin, Goldfine A. Inhibiting Serun Response Factor (SRF) to Improve Glycemic Control, filed June 6, 2008, and assigned U.S. Serial Number 61,059,597.
  • Patti ME, Wanzhu Jin, Goldfine A. Inhibiting Striated Muscle Activator of Rho Signaling (STARS), filed June 4, 2010, and assigned U.S. Serial Number 61351,479.